Used Pharmaceutical
Equipment For Sale

Used Pharmaceutical Equipment — Categories We Supply

SIGMA Process Equipment sources and trades in used pharmaceutical equipment for sale across the full range of solid-dosage, API, and biotech manufacturing processes. Our inventory covers machines used in pharmaceutical industry at both pilot and commercial scale — from individual units to partial line packages. Second hand pharmaceutical equipment is inspected and documented before listing.

Solid Dosage: Tablet Presses & Granulators

Used tablet press machines — rotary and single-punch types — are among the most actively traded items in used pharmaceutical machinery for sale. We carry a range of tooling sizes and compression forces. Used granulators (high-shear, fluid bed, roller compactors) and capsule filling machines are also stocked. These are core equipment used in pharmaceutical manufacturing for solid oral dosage forms.

Dryers for Pharmaceutical Use

Pharmaceutical drying covers several distinct technologies. Used fluid bed dryers handle wet granulation drying and coating. Used vacuum tray dryers and used freeze dryers (lyophilisers) are used for API and biological product drying. Used industrial dryers in GMP-compatible configurations — SS 316L contact surfaces, CIP-compatible — are sourced from pharma plant disposals. Vacuum tray dryer for pharma and tray dryer in pharmaceutical industry units are frequently available.

Reactors for Pharmaceutical Manufacturing

Used pharmaceutical manufacturing equipment regularly includes glass-lined reactors, stainless steel jacketed reactors, and Hastelloy reactors for API synthesis and extraction. Used reactors from pharma plants typically carry material certificates and can be supplied with available validation documentation. Sizes range from pilot-scale (50–500 L) to production scale (1,000–20,000 L).

Centrifuges for Pharmaceutical Production

Used pharmaceutical equipment for separation includes basket centrifuges (peeler and three-leg types) widely used in API crystallisation and filtration, and disc stack centrifuges for liquid-liquid separation in fermentation and extraction processes. Used centrifuges in pharmaceutical-grade stainless steel (316L) with documentation are available.

Mixers & Blenders

Pharmaceutical blending equipment includes V-blenders, ribbon blenders, double-cone blenders, and high-shear mixers. Blender used in pharmaceutical industry applications requires uniform mixing without product degradation. Used industrial mixers and blenders with GMP-compatible design are sourced from pharma plant closures. Planetary mixer used in pharmaceutical industry and high-shear granulators are also available.

Evaporators & Concentration Equipment

Thin film evaporators, falling film evaporators, and rotary evaporators are used in pharmaceutical extraction, solvent recovery, and API concentration. Used evaporators in pharmaceutical grade are available — specify solvent type, capacity, and required vacuum level when enquiring.

Vacuum Pumps & Ancillaries

A vacuum pump used in pharmaceutical industry must be oil-free or isolated from the process to avoid contamination. Dry-running vacuum pumps and liquid ring pumps from pharma facilities are occasionally available. Ask about ancillary equipment when making a main equipment enquiry.

Buying Used Pharmaceutical Machinery: Key Checks

• Material certificates — SS 316L for product-contact surfaces; 3.1 certificates (EN 10204) required for GMP applications.
• Surface finish — internal Ra ≤ 0.8 µm for pharmaceutical production; confirm or budget for re-polishing.
• CIP/SIP capability — verify spray ball coverage and drainage for cleaning validation.
• Instrumentation — check whether transmitters and control systems are calibrated and compatible with your site PLC.
• Existing validation records — available DQ/IQ/OQ records reduce re-qualification burden; ask what is available.

To enquire about used pharmaceutical machinery for sale, second hand pharma equipment, or used pharma machinery for sale, use the RFQ form below. We check stock and respond with condition details within 24 hours.

Common Requests We Fulfil

• Pharmaceutical equipment sales — direct sale of inspected units; no auction, no intermediary.
• Second hand pharmaceutical equipment for sale — sourced from plant closures across Europe and Asia, with available material certificates.
• Second hand pharma machinery / second hand pharma machinery for sale — tablet presses, granulators, dryers, reactors, centrifuges, and blenders.
• Old pharma machinery for sale — older-vintage units in sound mechanical condition, available at lower cost; ideal for pilot lines or developing-market facilities.
• Used pharmacy equipment / used pharmacy equipment for sale — compounding and dispensing-scale equipment as well as full production machinery.
• Equipment used in pharmaceutical lab — pilot-scale reactors, lab centrifuges, rotary evaporators, and vacuum dryers configured for R&D and scale-up.
• Pharmaceutical equipment used / pharmaceutical used equipment — all categories; contact us with your specific process requirement.